Ernestina (Stina) Schipani, M.D., Ph.D.

Principal Investigator

Professor, Department of Orthopaedic Surgery ; Professor, Department of Medicine and Endocrinology ; Professor, Department of Cell and Developmental Biology ; Faculty, Center for Organogenesis

Ernestina Schipani, M.D., Ph.D. is a Full Professor of Orthopedic Surgery, Medicine and Cell and Developmental Biology at University of Michigan-Medical School. She earned her M.D. and Ph.D. at St. Anna School of Advanced Studies-University of Pisa, Italy, then did her postdoctoral studies at MGH-Harvard Medical School, where she subsequently rose through the ranks and became Associate Professor. She was recruited to Indiana University-Medical School as a Full Professor of Internal Medicine. Early in her career, Dr. Schipani discovered that gain-of-function mutations of PTHR1 cause Jansen disease. Next, she pioneered the notion that hypoxia-driven pathways control skeletal development. Her laboratory has established novel principles in the broader fields of G-protein coupled receptors and hypoxia biology. She has received numerous national and international recognitions. NIH funds her research as an independent investigator since 1997. She is an ASCI member since 2005. In 2019, she was the recipient of the ASBMR Paula Stern Achievement Award. Dr. Schipani has authored more than 150 publications. CV, NIH-Bio page and PubMed

Zachary Tata, M.P.H.

Research Laboratory Specialist Associate

Zack manages logistics for the laboratory as well as the animal colony. Additionally, he pursues several research initiatives. Zack holds a Master of Public Health from Michigan State University, and has been with the laboratory since 2016

Christophe Merceron, Ph.D.

Research Investigator

Christophe obtained his Ph.D. from the University of Nantes – France and joined Dr. Schipani’s lab in 2012 to complete his post-doctoral training. Christophe’s work is focused on understanding the role of the Hypoxia Inducible Factor 2 (HIF2) in the regulation of bone mass accrual and homeostasis. For this work Christophe was the recipient of the Young Investigator Award from the ASBMR in 2018. He also enjoys outdoors activities, especially wildlife and landscape photography (see his Flickr website for many beautiful photos).

Mohd Parvez Khan, Ph.D.

Postdoctoral Fellow

Mohd Parvez Khan received his PhD from CDRI-JNU, India in 2016. In August 2016, he joined the Schipani Lab, where he works as a Postdoctoral research fellow. He is deciphering the role of Mitochondrial Transcription Factor A (TFAM) and Hypoxia Inducible Factor-alpha (HIF-1a) in skeletal development and bone mass accrual. When he is not in lab he enjoys the outdoors and fishing.

Perry Bruder, B.A.

Research Laboratory Technician Intermediate

Perry Bruder received his B.A. from Emory University in December 2018. In 2018 and 2019, he assisted the Hirsch Lab at UCLA studying the co-inoculation effects of plant growth-promoting bacteria. In June 2019, Perry joined the Schipani Lab, where he works as a research technician associate. Perry's excited to learn more about the hypoxia signaling pathway and skeletal development while developing his career in the biomedical sciences. In his free time, Perry enjoys spending time in nature and winter sports.

Elizabeth Wang

Undergraduate, LS & A

Elizabeth is currently a senior at the University of Michigan pursuing her Bachelor's degree in neuroscience. She joined the Schipani lab in 2017 as a research assistant and has learned a lot about the HIF2 signaling pathway since she has started. On her free time, Elizabeth likes practicing yoga, swimming, and spending time with family and friends.

Amy He

Undergraduate, LS & A

Amy is currently a freshman at the University of Michigan pursuing a Bachelor's degree in Pharmaceutical Sciences. She joined the Schipani lab in 2019 and is excited to learn about the Hypoxia Signaling Pathway. In her free time, Amy likes to play tennis and practice the piano.

Alumni at University of Michigan

Laura Mangiavini, M.D.

Research Fellow, 2011-2015

Tremika LeShan Wilson, B.S

Research Laboratory Technican, 2011-2014

Shreya Makkapati, B.S.

Undergraduate, LS & A, 2014-2017

Kavitha Ranganathan, M.D.

Research Fellow, Department of Plastic Surgery, Univ. of Mich., 2015-2016

Krishna Vemulapalli, B.S.

Undergraduate, LS & A, 2015-2016

Qing (Angela) Yao, Ph.D.

Postdoctoral Fellow, 2015-2017

Jia-rui Hu, M.D.

Research Fellow, 2015-2017

Lorenzo Sanesi, B.S.

Visiting Ph.D. Student, University of Bari, 2019